In women, with their much higher levels of estrogen, another hormone called progesterone normally balances estrogen, just as testosterone does in men. Estrogen dominance can lead to outbreaks of acne until DIM restores the balance. In men, it's normal for testosterone to keep the bad effects of estrogen in check. This is exactly what DIM achieves and why so many people (men as well as women) are taking it as a supplement. To maintain a sense of wellbeing, the body needs to break down estrogen into favourable metabolites rather than ones that cause feelings of malaise. It is also active in the menstrual cycle, which it helps to regulate by causing the lining of the uterus to thicken in preparation for potential reproduction.īecause estrogen is an integral part of the reproductive system its level fluctuates dramatically, often making it difficult for the body to cope either with an excess or a deficit of it. In women, estrogen (E2 in particular) plays a key role in the development of the so-called "secondary sex characteristics" including breasts, pubic and armpit hair, and wider hips. Estetrol - Is produced only during pregnancy by the fetal liver. Estriol - Is almost undetectable in women who are not pregnant. Estradiol - Is used in hormone replacement therapy (HRT) to treat menopausal symptoms 10x more potent than estrone 100x more than estriol. Estrone - Is a weak estrogen, less potent than estradiol, although it can metabolise into estradiol and become more active. Women have four main types, the second of which (E2) is the most relevant to supplement use. There are several forms of estrogen which occur naturally in the body.
Whereas men have more of the male sex hormone testosterone women have higher levels of estrogen.
The drug was safe and had no toxic effects on normal tissues and organs." (3)Įstrogen is the main female sex hormone, but, like testosterone, is actually present in both men and women. "In summary, the results of the study confirmed that the DIM effectively induced apoptosis of Nasopharyngeal Cancer (NPC) cells, and had a curative and preventative role in the development, and progression of NPC. DIM has been trialled and has potential use for preventing breast, uterine, and colorectal cancer (1) (2). It may also reduce the risk of rare types of cancer such as Nasopharyngeal Cancer (NPC) (3). That's because DIM has been found to have a whole range of health benefits, most notably for regulating estrogen metabolism, reducing estrogen dominance and achieving balance between two of the metabolites (intermediate end products) of estrogen: 2-hydroxy-estrone and 16-alpha-hydroxy-estrone.ĭIM's beneficial effect on estrogen metabolism is also linked to its efficacy in preventing or treating certain forms of cancer. These vegetables, and others including mustard greens, watercress and brussels sprouts, owe their reputation for bestowing health benefits largely to the science behind DIM. £29.99 120 Vegecaps Shop Now What Is DIM?ĭIM, or "diindolylmethane" (pronounced di-in-dol-leel methane), is a molecule of a compound called "indole-3-carbinol" (I3C) found in vegetables such as broccoli, cauliflower and kale.
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